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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Expression data from LSK cells from mice with knock-out of Ezh1 versus LSK control

ABSTRACT: Ezh1 is a protein member of PRC2. Ezh1 has been described as a functional repressor gene, such as its homologous Ezh2. We are investigating the role of Ezh1 in hematopoietic stem cells, aging, self-renewal and differentiation. We used microarrays to detail the global program of gene expression in LSK cells from mice with knocked-down expression of Ezh1. LSK cells from EZH1 knockout and control mice were marked and isolated by fluorescence-activated cell sorting. 2 replicates each.

ORGANISM(S): Mus musculus

SUBMITTER: Antonio Merchan

PROVIDER: E-GEOD-36288 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression profiling of LSK cells from Bmi1 cKO mice in hematopoiesis versus LSK control cells from WT mice

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Expression data from LSK cells from mice with knock-out of Ezh1 versus LSK control

Project description:Ezh1 is a protein member of PRC2. Ezh1 has been described as a functional repressor gene, such as its homologous Ezh2. We are investigating the role of Ezh1 in hematopoietic stem cells, aging, self-renewal and differentiation. We used microarrays to detail the global program of gene expression in LSK cells from mice with knocked-down expression of Ezh1.

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Divergent mechanisms of EZH1 regulation of heart development and regeneration [RNA-Seq]

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