Expression data from germinating conidia of Aspergillus niger in the presence of the polyene antibiotic natamycin.

ABSTRACT: The impact of natamycin on Aspergillus niger was analysed during 8 h of germination of conidia. Polarization, germ tube formation, and mitosis were inhibited in the presence of 3 M-BM-5M and 10 M-BM-5M of the anti fungal compound natamycin, while at 10 M-BM-5M also isotropic growth was affected. Natamycin did not have an effect on the decrease of internal microviscosity and the concomitant reduction on mannitol and trehalose levels. However, it did abolish the increase of intracellular levels of glycerol and glucose during the 8 h period of germination. Natamycin hardly affected the changes that occur in the RNA profile during the first 2 h of germination. During this time period, genes related to transcription, protein synthesis, energy and cell cycle and DNA processing were particularly

ORGANISM(S): Aspergillus niger

SUBMITTER: Martin van Leeuwen 

PROVIDER: E-GEOD-36440 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress