Strand-specific RNA-seq reveals ordered patterns of sense and antisense transcription in Bacillus anthracis

ABSTRACT: Although genome-wide transcriptional analysis has been used for many years to study bacterial gene expression, many aspects of the bacterial transcriptome remain undefined. A prominent example is antisense transcription, which has been observed in a number of bacteria, though the function of antisense transcripts, and their distribution across the bacterial genome, is still unclear. Single-stranded RNA-seq results revealed a widespread and non-random pattern of antisense transcription covering more than two-thirds of the B. anthracis genome. Our analysis revealed a variety of antisense structural patterns, suggesting multiple mechanisms of antisense transcription. The data revealed several instances of sense and antisense expression changes in different growth conditions, suggesting th

ORGANISM(S): Bacillus anthracis

SUBMITTER: Tim Read 

PROVIDER: E-GEOD-36506 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress