MRNA profiling during infection with H1N1 influenza A virus (A/Mexico/InDRE4487/H1N1/2009)

ABSTRACT: MicroRNAs (miRNAs) repress the expression levels of genes by binding to mRNA transcripts, acting as master regulators of cellular processes. Differential expression of miRNAs has been linked to viral-associated diseases involving members of the hepacivirus, herpesvirus, and retrovirus families. In contrast, limited biological and molecular information has been reported on the potential role of cellular miRNAs in the lifecycle of influenza A viruses (infA). In this study, we hypothesize that elucidating the miRNA expression signatures induced by low-pathogenic swine-origin influenza A virus (S-OIV) pandemic H1N1 (2009) and highly pathogenic avian-origin (A-OIV) H7N7 (2003) infections could reveal temporal and strain-specific miRNA fingerprints during the viral lifecycle, shedding important

ORGANISM(S): Homo sapiens

SUBMITTER: Victoria Svinti 

PROVIDER: E-GEOD-36553 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress