Gene expression analysis distinguishes tissue specific and gender related functions among adult Ascaris suum tissues.

ABSTRACT: Over a billion people are infected by Ascaris spp. intestinal parasites. We investigated gene expression by various tissues of adult A. suum, and used that information to help resolve basic functions of these tissues, basic biology of parasitism and functional aspects of nematode genomes. The A. suum genome was sequenced and assembled to allow generation of microarray elements. Expression of over 40,000 60-mer elements was investigated in a variety of tissues from both male and female adult worms. Nearly 50 percent of the elements for which signal was detected exhibited differential expression among different tissues. The unique profile of transcripts identified for each tissue clarified functional distinctions among tissues, such as chitin binding in the ovary and peptidase activity in t

ORGANISM(S): Ascaris suum

SUBMITTER: Makedonka Mitreva 

PROVIDER: E-GEOD-36690 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress