Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Expression data from control and colicin M treated E. coli MG1655 culture


ABSTRACT: Among colicin producing E. coli, colicin M producing strains are the most frequently present in natural populations. Bacteria must be able to sense and respond to unfavourable conditions, resulting in adaptive responses. To gain insight into colicin M ecological role and the purposes related to antimicrobial therapy, the effects of subinhibitory concentrations of colicin M on E. coli whole genome transcription was investigated. We used microarray analysis to follow differential gene expression in E. coli upon colicin M exposure. Colicin M inhibits peptidoglycan synthesis altering expression of genes involved in envelope stress, osmotic and other stresses, exopolysaccharide prodoction, biofilm formation, and cell motility. A sub-lethal concentration of colicin M was used to treat E. coli MG

ORGANISM(S): Escherichia coli str. K-12 substr. MG1655

SUBMITTER: simona kamensek 

PROVIDER: E-GEOD-37026 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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