JM43 cells grown aerobically in galactose and treated with Antimycin A
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ABSTRACT: In previous temporal studies, we found the anaerobic response was biphasic when cells growing in galactose medium were shifted from aerobiosis to anaerobiosis, consisting of an acute, transitory phase (<60 min) followed by a more chronic but delayed phase (> 1 generation), but largely monophasic (delayed, chronic phase only) when cells were shifted in glucose medium. Gene network and functional analyses revealed the acute phase was comprised of genes associated with the retooling of metabolism (respiro-fermentative to strictly fermentative) and balancing energy supply and demand. A similar pattern of gene expression is seen when cells encounter other “environmentally stressful” conditions. However, cells shifted to anaerobiosis on glucose, in which no catabolic rearrangement is required
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Kurt Kwast
PROVIDER: E-GEOD-3705 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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