Gene expression analysis of developing limbs

ABSTRACT: To evaluate geneexpression profile in developing joints vs adjacent growth plate in control and TGF-beta type II receptor conditional knock-out in limb mesenchyjme We obtained E14.5 autopods from two normal controls and two Tgfbr2Prx1KO littermate embryos. Samples were frozen in OTC and cryosectioned and subjected to laser-capture microdissection for RNA sampling for interzone, growth plate chondrocytes and interdigital tissue. RNas were subjected to microarray analysis

ORGANISM(S): Mus musculus

SUBMITTER: Anna Spagnoli 

PROVIDER: E-GEOD-37287 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress