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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gender dependent expression

ABSTRACT: Gender dependent gene expression in the kidney of 36 day old rats using the Affymetrix GeneChip rat expression set 230 array RAE230A. mixed model ANOVA using log2 transformed signal intensity of PM. Keywords: repeat Three rat strains Mhm, Us and MhmBN were examined. Three arrays were performed for each gender and strain combination. Total RNA from three rats was pooled for each array.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Li Li

PROVIDER: E-GEOD-3778 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Faster rates of post-puberty kidney deterioration in males is correlated with elevated oxidative stress in males vs females at early puberty.

Li Li L Boehn Susanne N SN Yu Xiaolei X Zhang Qingqin Q Kenzelmann Marc M Techel Dieter D Mohamed Salah A SA Jakob Petra P Kraenzlin Bettina B Hoffmann Sigrid S Gretz Norbert N

BMC genomics 20070709

<h4>Background</h4>Post-puberty deterioration of kidneys is more rapid in males than in females. To reveal the underlying molecular mechanisms for this difference, we analyzed gender-dependent gene expression in kidneys of three groups of 36 day-old rats.<h4>Results</h4>The number of genes exhibiting gender-dependent expression was highly influenced by the genetic background of the rat group examined. 373, 288 and 79 genes showed differential gene expression between males and females (p = 0.001) ...[more]

PMID: 17620128

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Gender dependent expression

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2006-12-31 | GSE3778 | GEO

Expression data from kidney of 36d old PKD/Mhm rats.

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Transcription profiling of rat kidney from male and female heterozygous PKD/Mhm and wild type animals

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Hypertensive Rat Kidney Study: Gender-Selective Responses to Salt in Dahl-Iwai & Sprague-Dawley Rats

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Toxicogenomic Analysis of Gender, Chemical, and Dose Effects in Livers of TCDD- or Aroclor 1254-Exposed Rats

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