VP963/DK1622

ABSTRACT: Phosphate regulation is complex in the developmental prokaryote Myxococcus xanthus, and requires at least three previously characterized two-component systems (TCS), designated PhoR1-PhoP1, PhoR2-PhoP2, and PhoR3-PhoP3. We report here the identification and characterization of a member of a fourth TCS, designated PhoP4, which shows high sequence similarity to the other three M. xanthus PhoP response regulators. PhoP4 is an orphan response regulator that was identified by yeast 2-hybrid screen as a possible interacting partner of PhoR2. phoP4 insertion mutation and in-frame deletion strains were constructed and assessed for developmental and phosphatase phenotypes, and then compared with the phenotypes previously reported for a _phoR2-phoP2 strain. The data indicate that the phoP4 mutat

ORGANISM(S): Myxococcus xanthus

SUBMITTER: Mitchell Singer 

PROVIDER: E-GEOD-3795 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress