Methylation in Taiwanese HCC tumor and adjacent tissues

ABSTRACT: We analyzed tumor and adjacent non-tumor tissues from 62 Taiwanese HCC cases using Illumina HumanMethylation 27 chips. After Bonferroni adjustment, a total of 2,324 CpG sites significantly differed in methylation level, with 684 CpG sites significantly hypermethylated and 1,640 hypomethylated in tumor compared to non-tumor tissues. Array data were validated with pyrosequencing in a subset of 5 of these genes; correlation coefficients ranged from 0.92 to 0.97. 62 tumor and 62 adjacent non tumor tissues

ORGANISM(S): Homo sapiens

SUBMITTER: Regina Santella 

PROVIDER: E-GEOD-37988 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress