Gene Expression in Postnatal Mouse Kidney Development

ABSTRACT: INTRODUCTION AND OBJECTIVE: Obstruction and other processes that lead to renal damage can have different effects in adult versus developing kidneys. These differences are important for understanding pathophysiology, but also could influence selection of biomarkers used for detection of renal damage that could be used to guide intervention. In mice, significant renal development occurs postnatally, providing a model for understanding kidney development. To date, gene expression changes that occur mouse kidney growth and development postnatally have been poorly characterized. We describe here a comprehensive gene expression of the developing mouse kidney based on microarray profiling. METHODS: C57BL/6 mice were sacrificed and kidneys were harvested at embryonic day E19.5, and postnatal da

ORGANISM(S): Mus musculus

SUBMITTER: Bo Wu 

PROVIDER: E-GEOD-38025 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress