Transcription profiling of S. cerevisiae H2B K6,11,16,17,21,22G mutant vs. wild type to investigate the role of H2B N-terminal domain in transcription

ABSTRACT: Histone H2B was mutated to give H2B K6,11,16,17,21,22G. Total RNA from three replicate cultures of wild-type and mutant was isolated and the expression profiles were determined using Affymetrix arrays. Comparisons between the sample groups allow the identification of genes regulated by H2B N-terminal acetylated lysine residues. Experiment Overall Design: mutant compared to wild-type, 3 replicates

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: John Wyrick 

PROVIDER: E-GEOD-3803 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress