Genomic and phenotypic alterations of the neuronal-like cells derived from the human embryonal carcinoma stem cells (NT2) caused by exposure to the organophosphorus compounds paraoxon and mipafox

ABSTRACT: hNT2 under neurodifferentiation were exposed during 4 days to 1 µM of the non-neuropathic organophosphorus compound paraoxon and 5 µM of the neuropathic organophosphorus compound and afterwards transcriptomics were analysed and compared regarding control non-exposed cells Exposure to paraoxon caused alteration of 137 genes while only a single gene was altered after exposure to mipafox Comparing two experimental conditions: control versus paraoxon or mipafox exposed cells. Three biological replicates.

ORGANISM(S): Homo sapiens

SUBMITTER: Marco Fabbri 

PROVIDER: E-GEOD-38050 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress