Transcription profiling of S. cerevisiae exposed to the sudden addition of glucose - short term perturbation
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Jean-Marc Daran
PROVIDER: E-GEOD-3821 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation.
Kresnowati M T A P MT van Winden W A WA Almering M J H MJ ten Pierick A A Ras C C Knijnenburg T A TA Daran-Lapujade P P Pronk J T JT Heijnen J J JJ Daran J M JM
Molecular systems biology 20060912
Within the first 5 min after a sudden relief from glucose limitation, Saccharomyces cerevisiae exhibited fast changes of intracellular metabolite levels and a major transcriptional reprogramming. Integration of transcriptome and metabolome data revealed tight relationships between the changes at these two levels. Transcriptome as well as metabolite changes reflected a major investment in two processes: adaptation from fully respiratory to respiro-fermentative metabolism and preparation for growt ...[more]
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