Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Simone de Jong
PROVIDER: E-GEOD-38484 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
de Jong Simone S Boks Marco P M MP Fuller Tova F TF Strengman Eric E Janson Esther E de Kovel Carolien G F CG Ori Anil P S AP Vi Nancy N Mulder Flip F Blom Jan Dirk JD Glenthøj Birte B Schubart Chris D CD Cahn Wiepke W Kahn René S RS Horvath Steve S Ophoff Roel A RA
PloS one 20120627 6
Despite large-scale genome-wide association studies (GWAS), the underlying genes for schizophrenia are largely unknown. Additional approaches are therefore required to identify the genetic background of this disorder. Here we report findings from a large gene expression study in peripheral blood of schizophrenia patients and controls. We applied a systems biology approach to genome-wide expression data from whole blood of 92 medicated and 29 antipsychotic-free schizophrenia patients and 118 heal ...[more]