Gene regulatory networks involved in early embryonic Silurana tropicalis development

ABSTRACT: Gene set and sub-network enrichment analysis provides an integrated approach for identifying gene regulatory networks underlying development. Anuran development is a coordinated process, and levels of mRNA are first dominated by maternally deposited genes, followed by active transcription of embryonic genes as the embryo undergoes morphogenesis and organ formation. The objectives of this study were to characterize early gene regulatory networks underlying Silurana tropicalis development. A custom Agilent 4 x 44 K microarray was developed to characterize networks during early development (1, 17, 36, 96 hpf). Cluster analysis revealed that each stage showed unique gene expression profiles and that 1 hpf was most different than the other three stages. There were > 8000 unique gene probes

ORGANISM(S): Xenopus (Silurana) tropicalis

SUBMITTER: Christopher Martyniuk 

PROVIDER: E-GEOD-38576 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress