Array-based transcriptional analysis of Clostridium sporogenes during germination, cell outgrowth and vegetative life

ABSTRACT: The members of the genus Clostridium, such as the other spore-forming anaerobic bacteria, have a complex and strictly regulated life-cycle but very little is known about genetic pathways involved at different stages. Clostridium sporogenes, Gram positive bacterium usually involved in food spoilage and frequently isolated from late blowed cheese is genetically indistinguishable from proteolytic Clostridium botulinum and is the non-neurotoxigenic counterpart often used as exemplar for the toxic subtypes. In this work we have performed a microscopy study combined with a custom array-based analysis of C. sporogenes cycle, from dormant spores to early stationary phase. We identified in spores a total of 211 transcripts validating the ipothesis that mRNAs are abundant and strikingly different f

ORGANISM(S): Clostridium sporogenes

SUBMITTER: Daniela Bassi 

PROVIDER: E-GEOD-38619 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress