MicroRNA expression profiles associated with anti-schistosome features in Microtus fortis

ABSTRACT: Microtus fortis (M. fortis) is the only mammal in which the growth, development and maturation of schistosomes (Schistosoma japonicum) is prevented, resulting in the failure of the parasite to mature and complete its life cycle. MicroRNAs (miRNAs) are a class of endogenous, non-coding small RNAs, has been found to introduce a whole new layer of gene regulation in eukaryotes. The anti-schistosomiasis mechanosm of M. fortis may require the participation of miRNA-mediated gene expression. In the present study, the difference pathological change of different tissue such as liver, spleen and lung of M. fortis were observed by using haematoxylin-eosin staining. Also, the miRNA expression in different tissue of M. fortis and mice before challenge and 10 days post-infection with schistosomes were

ORGANISM(S): Mus musculus

SUBMITTER: hongxiao han 

PROVIDER: E-GEOD-38802 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress