Gene expression profiles of induced pluripotent mesenchymal stromal cells [Affymetrix]

ABSTRACT: Reprogramming of somatic cells into induced pluripotent stem cells (iPSC) is an epigenetic phenomenon. We have reprogrammed mesenchymal stromal cells (MSC) from human bone marrow by retrovirus-mediated overexpression of OCT-3/4, SOX2, c-MYC, and KLF4. This series summarizes gene expression profiles of eight iP-MSC clones derived from three different donors. These datasets were subsequently used for PluriTest analysis (Muller FJ, Schuldt B et al., Nat. Methods 2011; 8: 315-317) demonstrating that all iP-MSC clones were clearly associated with pluripotent cells. Eight iP-MSC clones derived from three different donors.

ORGANISM(S): Homo sapiens

SUBMITTER: Wolfgang Wagner 

PROVIDER: E-GEOD-38806 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress