PrPC-dependent gene expression and cell signalling signature in Neuro2a cells. Role on mitogenic stimulation and cell morphology.

ABSTRACT: In this work we present the PrPC-dependent gene expression signature in N2A cells and its implication on the most overrepresented functions; cell cycle, cell growth and proliferation and cell morphology. To evaluate the genes whose transcription was regulated after Prnp modulation, RNA samples were analyzed with Illumina mouse whole genome beadarrays. cell type comparison; genetic modification; RNA interference

ORGANISM(S): Mus musculus

SUBMITTER: Lauro Sumoy 

PROVIDER: E-GEOD-38887 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress