Transcription profiling of human heterozygous carriers of Nijmegen Breakage Syndrome reveals distinct gene expression phenotype.

ABSTRACT: By comparing the expression levels of genes between carriers of Nijmegen Breakage Syndrome and non-carriers, we showed that NBS carriers have a distinct gene expression phenotype. Experiment Overall Design: Gene expression analysis using Affymetrix Human Focus arrays; comparison of expression levels of genes using t-statistic and identification of genes that allow classification of individuals as carriers or non-carriers by linear discriminant analysis.

ORGANISM(S): Homo sapiens

SUBMITTER: Michael Morley 

PROVIDER: E-GEOD-3894 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress