TRNA fragment profiling in CLP1 mutant (kinase-dead) mice

ABSTRACT: Loss of CLP1 activity results in the accumulation of novel sets of small RNA fragments derived from aberrant processing of tyrosine pre-tRNA. Such tRNA fragments sensitize cells to oxidative stress-induced p53 activation and p53-dependent cell death. 2 samples, Wt and Clp1(k/k), no replicates

ORGANISM(S): Mus musculus

SUBMITTER: Javier Martinez 

PROVIDER: E-GEOD-39275 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress