Contribution of the mammary epithelial cell to the immune response during early stages of a bacterial infection to Staphylococcus aureus in goats

ABSTRACT: Mastitis is an inflammation of the mammary gland (MG), usually due to bacterial infection. Although considerable attention has been paid to this economically important disease, the early stages of the host response remain poorly defined. In particular, it is unclear how mammary epithelial cells (MEC), a first barrier against pathogens, respond to infection. Indeed, it is difficult to differentiate between the contributions of MEC and infiltrating immune cells to gene expression profiles of mammary tissue during mastitis. The current investigation examines the response of MEC at the early stage of infection using a non invasive RNA sampling method taking advantage of the presence of cytoplasmic crescents contained in milk fat globules. We have recently shown that, in goats, Milk Fat Globule

ORGANISM(S): Capra hircus

SUBMITTER: Pauline Brenaut 

PROVIDER: E-GEOD-39315 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress