Copy Number Data from Archival Leiomyosarcoma

ABSTRACT: Soft tissue sarcomas (STS) often present a significant diagnostic challenge as many STS bear histologic resemblance, but are known to have very different clinical and biologic characteristics. Some STS subtypes are characterized by specific genetic abnormalities and this has helped in their classification, diagnosis and even treatment. However, a large majority of STS have no known specific genetic aberrations even though they almost always have highly aberrant karyotypes. We therefore hypothesize that the latter subgroup of STS bear genetic abnormalities that are sub-type specific, but as yet unidentified. High-resolution mapping of copy number aberrations in cancer genomes is a valuable way of identifying recurrent genomic changes that could be of pathogenetic significance. Traditionall

ORGANISM(S): Homo sapiens

SUBMITTER: Abdulazeez Salawu 

PROVIDER: E-GEOD-39663 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress