Amniotic fluid-derived cells: genome-wide expression in early and late cultures

ABSTRACT: Amniotic fluid stem cells (AFSCs) are of interest in regenerative medicine as a non-controversial and potentially 'abundant' source of stem cells. Progress has been made in understanding amniotic fluid stem cell biology, and amniotic fluid-derived cells have been induced to form neurons, osteoblasts, muscle cells, and others. Our study evaluates change in the genome-wide expression profile of amniotic fluid stem cells during in-vitro culture, using Affymetrix U133 Plus 2.0 microarray chips. We found that only 3.08% of gene probes were differentially expressed from early to late passage of AFSC culture. The differentially expressed genes were related to biological processes or cellular function - including transcription factors, protein kinases, and cytokines/growth factors. Other gene-sets

ORGANISM(S): Homo sapiens

SUBMITTER: Ashwin Jadhav 

PROVIDER: E-GEOD-39839 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress