Comparative Transcriptomic Analysis of Salmonella in Desiccation

ABSTRACT: To explore the mechanisms of Salmonella desiccation resistance, we studied the transcriptomic responses in Salmonella Tennessee (Tennessee), using S. Typhimurium LT2 (LT2), a strain weakly resistant to desiccation, as a reference strain. In response to 2 h air-drying at 11% equilibrated relative humidity, approximately one-fourth of the ORFs in the Tennessee genome and one-fifth in LT2 were differentially expressed (> 2-fold). Among all differentially expressed functional groups (>5-fold) in both strains, the expression fold change associated with fatty acid metabolism was the highest, and constituted 51 and 35% of the total expression fold change in Tennessee and LT2, respectively. Tennessee showed greater changes in expression of genes associated with stress response and envelope modific

ORGANISM(S): Salmonella enterica subsp. enterica serovar Tennessee

SUBMITTER: Haiping Li 

PROVIDER: E-GEOD-40146 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress