Clostridium thermocellum ATCC 27405 Transcriptomic Profiles after Exposure to Ethanol, Furfural and Heat Stress

ABSTRACT: The thermophilic anaerobe Clostridium thermocellum is a candidate consolidated bioprocessing biocatalyst for the conversion of lignocellulosic biomass into ethanol. The microorganism expresses enzymes for both cellulose solubilization and fermentation to produce lignocellulosic ethanol making it a good candidate for industrial biofuel production. Intolerance to stresses routinely encountered during industrial fermentations may hinder the commercial development of this organism. A recently published study by Yang et al., (2012) characterized the physiological and regulatory response of C. thermocellum to ethanol supplementation. Significant changes in nitrogen metabolism and an accumulation of carbon sources were identified, revealing potential targets for metabolic engineering. In the cu

ORGANISM(S): Clostridium thermocellum ATCC 27405

SUBMITTER: Charlotte Wilson 

PROVIDER: E-GEOD-40402 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress