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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Microarray analysis of toxicogenomic effect of Ortho-Benzyl-Para-Chloro Phenol (OBPCP) on Staphylococcus aureus.

ABSTRACT: Global gene expression analysis of Staphylococcus aureus following Ortho-Benzyl-Para-Chloro Phenol (OBPCP) treatment using Affymetrix GeneChip arrays. Results from this study provide insight into the molecular mechanisms underlying the cellular response of Staphylococcus aureus to OBPCP. We conducted five independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of Ortho-Benzyl-Para-Chloro Phenol(OBPCP). Fold change was calculated as a ration between the signal averages of five untreated (control) and five OBPCP-treated (experimental) cultures after 0, 10 and 60 min exposure time.

ORGANISM(S): Staphylococcus aureus

SUBMITTER: Prashanthi Mulinti

PROVIDER: E-GEOD-40448 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Microarray analysis of toxicogenomic effect of Ortho-Benzyl-Para-Chloro Phenol (OBPCP) on Staphylococcus aureus.

Project description:Global gene expression analysis of Staphylococcus aureus following Ortho-Benzyl-Para-Chloro Phenol (OBPCP) treatment using Affymetrix GeneChip arrays. Results from this study provide insight into the molecular mechanisms underlying the cellular response of Staphylococcus aureus to OBPCP.

2013-01-01 | GSE40448 | GEO

Microarray analysis of toxicogenomic effect of Para-Tertiary Amyl Phenol (PTAP) on Staphylococcus aureus.

Project description:Global gene expression analysis of Staphylococcus aureus following Para-Tertiary Amyl Phenol (PTAP) treatment using Affymetrix GeneChip arrays. Results from this study provide insight into the molecular mechanisms underlying the cellular response of Staphylococcus aureus to PTAP. We conducted four independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of Para-Tertiary Amyl Phenol (PTAP). Fold change was calculated as a ration between the signal averages of five untreated (control) and five PTAP-treated (experimental) cultures after 0, 10 and 60 min exposure time.

2013-01-01 | E-GEOD-40449 | biostudies-arrayexpress

Staphylococcus aureus

Project description:Microarray analysis of toxicogenomic effect of Ortho-Benzyl-Para-Chloro Phenol (OBPCP) on Staphylococcus aureus.

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Project description:Comparative analysis of the toxicogenomic effects of Ortho-Benzyl-Para-ChloroPhenol (OBPCP) and Para-Tertiary AmylPhenol (PTAP) on Staphylococcus aureus

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Microarray Analysis of Toxicogenomic Effects of Ortho-Phenylphenol on Staphylococcus aureus

Project description:In the present study, we employed Affymetrix Staphylococcus aureus GeneChip arrays to investigate the dynamics of global gene expression profiles during the cellular response of Staphylococcus aureus to Ortho-Phenylphenol, which involved initial growth inhibition and metabolism. Keywords: Time course We conducted five independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of Ortho-Phenylphenol. We calculated fold change as the ratio between the signal averages of five untreated (control) and five ortho-phenylphenol-treated (experimental) cultures for 0, 20 and 60 min exposures.

2008-04-01 | E-GEOD-10605 | biostudies-arrayexpress

Comparative analysis of the toxicogenomic effects of Ortho-Benzyl-Para-ChloroPhenol (OBPCP) and Para-Tertiary AmylPhenol (PTAP) on Staphylococcus aureus

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-01-01 | E-GEOD-40450 | biostudies-arrayexpress

Human gastric mucosa: 3 paired hTERT-negative para cancerous tissue (Control) vs. hTERT-positive gastric cancer tissue

Project description:The lncRNA expression profiles in three pairs of hTERT-positive gastric cancer tissue sand hTERT-negative para-cancerous tissues. The para-cancerous tissue is at least 5cm away from the cancer tissue. The expression of hTERT of identified by immunohistochemistry before RNA extraction for lncRNA assay. LncRNAs/mRNAs in 3 gastric cancer tissue and 3 paired para-cancerous tissue (Control) by microarray using Arraystar Human LncRNA Microarray v2.0

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Microarray analysis of toxicogenomic effect of Para-Tertiary Amyl Phenol (PTAP) on Staphylococcus aureus.

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Project description:Staphylococcus aureus is one of the most important pathogens in humans and animals, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. Rhein, a natural plant product, has potential antimicrobial activity against Staphylococcus aureus. We employed Affymetrix Staphylococcus aureus GeneChipsTM arrays to investigate the global transcriptional profiling of Staphylococcus aureus ATCC25923 treated with rhein. Results provided insight into mechanisms involved in rhein - Staphylococcus aureus interactions. Keywords: rhein response Staphylococcus aureus cells were exposed for 45 minutes to rhein at concentration of 8 Âµg/ml (1/2Ã MIC), 6 samples including 3 control samples are analyzed.

2010-06-10 | E-GEOD-8135 | biostudies-arrayexpress

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