Intestinal Salmonella Typhimurium infection leads to miR-29a induced Caveolin 2 regulation [mRNA]

ABSTRACT: The host response to S.typhimurium infections in ileum was studied after infection of piglets. mRNA and miRNA expression studies were performed to identify interactions of miRNAs and regulated mRNAs in context of mammalian intestinal Salmonella infection using a piglet model. Intestinal samples (~ 2 cm circle segments) were taken at time points 3h, 3d and 28d post infection from ileum of ten S.typhimurium infected piglets (S), ten S.typhimurium infected piglets and additional treated with probiotic strain E.faecium NCIMB 10415 (SP) and five healthy control piglets(C) (EUROC x Pietrain). The piglets were weaned at the age of 28 days and infected with S. typhimurium. Samples were quick-frozen in liquid nitrogen and stored at -80 M-BM-0C. In order to obtain representative measurements in each

ORGANISM(S): Sus scrofa

SUBMITTER: Soroush Sharbati 

PROVIDER: E-GEOD-40804 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress