Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

A global transcriptome analysis of keratinocytes upon suppression of endogenous microRNA-31


ABSTRACT: MiR-31 is one of the most highly overexpressed miRNAs in psoriasis skin; however, its biological role in the disease has not been studied. Here we show that miR-31 is markedly overexpressed in psoriasis keratinocytes. To study the biological role of miR-31 in keratinocytes, we transfected miR-31 hairpin inhibitor (anti-miR-31) into primary human keratinocytes to inhibit endogenous miR-31. We performed a global transcriptome analysis of keratinocytes upon suppression of endogenous miR-31 using Affymetrix arrays. Expression profiling of primary human keratinocytes transfected with 10nM miR-31 hairpin inhibitor (anti-miR-31) or control hairpin RNA (anti-miR-Ctrl) for 48 hours (biological triplicates in each group) was performed using the Affymetrix GeneTitan system.

ORGANISM(S): Homo sapiens

SUBMITTER: Ning Xu 

PROVIDER: E-GEOD-41905 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2011-09-19 | E-GEOD-30355 | biostudies-arrayexpress
2012-10-30 | GSE41905 | GEO
2010-11-24 | E-GEOD-24767 | biostudies-arrayexpress
2008-06-11 | E-GEOD-11181 | biostudies-arrayexpress
2023-02-06 | PXD029030 | Pride
2012-03-07 | E-GEOD-36287 | biostudies-arrayexpress
2014-01-01 | E-MTAB-1739 | biostudies-arrayexpress
2013-12-31 | GSE50099 | GEO
2013-12-31 | E-GEOD-50099 | biostudies-arrayexpress
2011-10-11 | E-GEOD-32620 | biostudies-arrayexpress