Cerebellar Granule Neuron Temporal-NFI Microarray Data

ABSTRACT: Dendrite and synapse development are critical for establishing appropriate neuronal circuits, and disrupted timing of these events can alter connectivity leading to disordered neural function. In early postnatal development of cerebellar granule neurons (CGNs), the expression of many genes is temporally regulated. Further, NFI (Nuclear Factor I) proteins have been shown to play important roles in the regulation of gene expression in developing CGNs. To identify NFI-regulated genome-wide targets involved in late maturation of mouse CGNs, we performed two groups of microarray expression analysis: (1) temporal expression arrays using 1.5 and 6 day cultures of mouse CGNs representing immature and more mature CGNs, respectively, which identified 844 Temporal-Up or Down genes; and (2) NFI-regula

ORGANISM(S): Mus musculus

SUBMITTER: Baojin Ding 

PROVIDER: E-GEOD-42018 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress