Notch Pathway Activation Targets AML Cell Homeostasis and Differentiation: THP1 cell line

ABSTRACT: Expression data from untreated or Dll4-Fc treated THP1 cell line. We used Dll4-Fc stimulation of AML cells to study whether Notch activation has an impact on AML. We analyzed THP1 cell line in vitro treated with Dll4-Fc or vehicle control to determine genes affected by Notch activation. THP1 cell line was cultured on plate coated with 30 nM Dll4-Fc or vehicle for 48 hours prior to RNA extraction and hybridization to Human Genome U133 Plus 2.0 Affymetrix arrays.

ORGANISM(S): Homo sapiens

SUBMITTER: Camille Lobry 

PROVIDER: E-GEOD-42259 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress