Dataset Information
Full genome expression profiling of primary colorectal cancer (CRC)
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Paul Roepman
PROVIDER: E-GEOD-42284 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial-to-mesenchymal transition.
International journal of cancer 20130913 3
In most colorectal cancer (CRC) patients, outcome cannot be predicted because tumors with similar clinicopathological features can have differences in disease progression and treatment response. Therefore, a better understanding of the CRC biology is required to identify those patients who will benefit from chemotherapy and to find a more tailored therapy plan for other patients. Based on unsupervised classification of whole genome data from 188 stages I-IV CRC patients, a molecular classificati ...[more]
