Transcription profiling of mouse thymocytes from ild type or RORg-/- animals
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: NIEHS Microarray Group
PROVIDER: E-GEOD-4248 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
NABP1, a novel RORgamma-regulated gene encoding a single-stranded nucleic-acid-binding protein.
Kang Hong Soon HS Beak Ju Youn JY Kim Yong-Sik YS Petrovich Robert M RM Collins Jennifer B JB Grissom Sherry F SF Jetten Anton M AM
The Biochemical journal 20060701 1
RORgamma2 (retinoid-related orphan receptor gamma2) plays a critical role in the regulation of thymopoiesis. Microarray analysis was performed in order to uncover differences in gene expression between thymocytes of wild-type and RORgamma-/- mice. This analysis identified a novel gene encoding a 22 kDa protein, referred to as NABP1 (nucleic-acid-binding protein 1). This subsequently led to the identification of an additional protein, closely related to NABP1, designated NABP2. Both proteins cont ...[more]
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