V. salmonicida wild type strain LFI1238 and isogenic DlitR mutant grown in suspension in SWT medium

ABSTRACT: Quorum sensing (QS) is a cell density regulated communication system that bacteria use to coordinate activities, including biofilm formation, involved in colonization and pathogenesis. We have previously shown that inactivation of the QS master regulator LitR attenuates the Vibrio (Allivibrio) salmonicida strain LFI1238 in a fish model. In this work we show that LFI1238 as well as a panel of naturally occurring V. salmonicidia strains are poor biofilm producers. Inactivation of litR strongly enhances medium and temperature dependent adhesion, rugose colony morphology and biofilm formation. Chemical treatment and scanning electron microscopy of the biofilm identified an extracellular matrix consisting mainly of protein filaments and polysaccharides. Further, microarray analysis of planktoni

ORGANISM(S): Aliivibrio salmonicida LFI1238

SUBMITTER: Espen Robertsen 

PROVIDER: E-GEOD-42994 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress