Comparison of the expression profiles of the 630E strain and a sigG mutant after 19h of growth

ABSTRACT: Compartment-specific control of gene expression during Bacillus subtilis sporulation is governed by a cascade of four sigma factors, sigmaF and sigmaG in the forespore and sigmaE and sigmaK in the mother cell. In this work, we combined transcriptional analyses and transcriptional start site mapping to define the sigmaF, sigmaE, sigmaG and sigmaK regulons in Clostridium difficile. A total of about 225 genes were under the control of these sigma factors: 25 in the sigmaF regulon, 97 sigmaE-dependent genes, 50 sigmaG-governed genes and 56 genes specifically controlled by sigmaK. A significant fraction of genes in each regulon are of unknown function and we can propose new candidates for spore coat proteins synthesized under the control of sigmaE and sigmaK among proteins previously detected i

ORGANISM(S): [Clostridium] difficile

SUBMITTER: Monot Marc 

PROVIDER: E-GEOD-43200 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress