Gene expression profile changes in HDAC6 knockdown HT1080 cells cells after TLR3 stimulation

ABSTRACT: TLR3 stimulation by extracellular dsRNA (e.g. polyIC) induces expression of numerous genes. The knockdown of HDAC6 prior to TLR3 stimulation leads to an ablation of expression of IRF-3-dependent genes. Total RNA extracted from HT1080 cells expressing control-shRNA or HDAC6-shRNA, after 6 h of treatment with dsRNA (polyIC), compared to untreated controls

ORGANISM(S): Homo sapiens

SUBMITTER: Ganes Sen 

PROVIDER: E-GEOD-43218 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress