Caco-2 incubation with different doses of Lactobacillus

ABSTRACT: Background: Lactobacillus plantarum is found in a variety of fermented foods and as such, consumed for centuries. Some strains are natural inhabitants of the human gastro-intestinal tract and like other Lactobacillus species, L. plantarum has been extensively studied for its immunomodulatory properties and its putative health-promoting effects (probiotic). Being the first line of host defense intestinal epithelial cells (IEC) are key players in the recognition and initiation of responses to gut microorganisms. Results: Using high-density oligonucleotide microarrays we examined the gene expression profiles of differentiated Caco-2 cells exposed to various doses of L. plantarum. In addition, the effects were correlated to monolayer permeability studies and measurement of lactic acid product

ORGANISM(S): Homo sapiens

SUBMITTER: Sonia Pavan 

PROVIDER: E-GEOD-4325 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress