HEPATIC GENE EXPRESSION PATTERNS IN JUVENILE TURBOTS (Scophthalmus maximus) AFTER EXPOSURE TO NO2 FUEL OIL AND TO STYRENE (PRAGMA, a pragmatic and integrated approach for the evaluation of environmental impact of oil and chemical spills at sea)

ABSTRACT: Accidental spills of chemical or oil tankers such as Levoli Sun or Prestige have recently impacted the European seas. The analysis of the genes regulated by exposure to spilled chemical substances could help elucidating adaptatory and compensatory pathways that may participate in pathogenesis in marine biota. Hepatic expression profiles of male juvenile S. maximus exposed to a nº2 fuel-oil (FO) and to styrene were studied employing a turbot custom microarray containing 2715 3’-UTR biassed single-sequences, many of them unannotated. Hybridisations identified 169 and 293 genes significantly regulated after 3 and 14 days of exposure to FO, respectively. Typical PAH responsive genes such as AhRR, ARNT2, CYP1A1 and GST were significantly upregulated. Exposure significantly affected genes inv

ORGANISM(S): Scophthalmus maximus

SUBMITTER: Ibon Cancio 

PROVIDER: E-GEOD-43355 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress