Expression data from mouse T cells after CLIP (Crosslinking immunoprecipitation) procedures (microRNA)

ABSTRACT: Molecular networks based on genome-wide mRNA and miRNA expression in activated T cells are integrated by co-regulation with miRNA and protein-coding genes during immune responses, however, accurate prediction of miRs and their targets remains a challenge. Furthermore, the specific changes in the expression of miRNAs and/or mRNAs in allogeneic activated T cells during HCT would be distinct from those responding to non-specific stimulation. Recently, Ago-CLIP has been demonstrated to provide a robust platform for identification of precise miRNA-mRNA interactions by definitively distinguishing direct from indirect miRNA-target interactions. We utilized CLIP procedure followed by screening with standard microarray platforms for miRNA and mRNA transcripts to demonstrate the miR-mRNA landscape a

ORGANISM(S): Mus musculus

SUBMITTER: yaping sun 

PROVIDER: E-GEOD-43634 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress