Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Interleukin 1 receptor regulates miRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Sarah Labib

PROVIDER: E-GEOD-43688 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

IL-1 receptor regulates microRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation.

Halappanavar Sabina S Nikota Jake J Wu Dongmei D Williams Andrew A Yauk Carole L CL Yauk Carole L CL Stampfli Martin M

Journal of immunology (Baltimore, Md. : 1950) 20130225 7

Although microRNA-135b (miR-135b) is known to be associated with cancer, with recent work showing that it is massively induced in the pulmonary tissues of mice challenged with nanoparticles suggests a critical role for this microRNA in mediating inflammatory response. In this study, we investigated the expression and function of miR-135b in mice exposed to cigarette smoke or nontypeable Haemophilus influenzae (NTHi). Exposure to both cigarette smoke and NTHi elicited robust lung inflammation, bu ...[more]

PMID: 23440414

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Dataset Information

Interleukin 1 receptor regulates miRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation

Publications

IL-1 receptor regulates microRNA-135b expression in a negative feedback mechanism during cigarette smoke-induced inflammation.

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