Cellular source and mechanisms of high transcriptome complexity in the mammalian testis (RNA-Seq cells)

ABSTRACT: Understanding the extent of genomic transcription and its functional relevance is a central goal in genomics research. However, detailed genome€wide investigations of transcriptome complexities in major mammalian organs  and  their  underlying  cellular sources, transcriptional mechanisms, and functional relevance have been scarce. Here we first show, using extensive RNA€seq data, that transcription of both functional and nonfunctional genomic elements is substantially more widespread in the testis than in other organs across representative mammals. By scrutinizing the transcriptomes of all main testicular cell types in the mouse, we then reveal that meiotic  spermatocytes and especially post€meiotic round spermatids have remarkably diverse transcriptomes, which explains the high transc

ORGANISM(S): Mus musculus

SUBMITTER: Magali Soumillon 

PROVIDER: E-GEOD-43717 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress