Identification of nucleosome positions at hox TSSs during zebrafish early embryonic development
Ontology highlight
ABSTRACT:
ORGANISM(S): Danio rerio
SUBMITTER: Steven Weicksel
PROVIDER: E-GEOD-43758 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Dynamic nucleosome organization at hox promoters during zebrafish embryogenesis.
Weicksel Steven E SE Xu Jia J Sagerström Charles G CG
PloS one 20130509 5
Nucleosome organization at promoter regions plays an important role in regulating gene activity. Genome-wide studies in yeast, flies, worms, mammalian embryonic stem cells and transformed cell lines have found well-positioned nucleosomes flanking a nucleosome depleted region (NDR) at transcription start sites. This nucleosome arrangement depends on DNA sequence (cis-elements) as well as DNA binding factors and ATP-dependent chromatin modifiers (trans-factors). However, little is understood about ...[more]
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