Role of GM-NM-1(olf) in Familial and Sporadic Adult-Onset Primary Dystonia

ABSTRACT: Gene expression studies were performed to identify pathways possibly dysregulated by mutant in the gene GM-NM-1(olf). These experiments employed RNA derived from lymphoblastoid cell lines established for 4 affected carriers and 4 non-carriers. In comparison to endogenous control and other dystonia-associated genes, GNAL was expressed at relatively low levels in lymphoblastoid cell lines. Comparison of whole blood expression profiles of mutation carrying dystonia patients with normal controls

ORGANISM(S): Homo sapiens

SUBMITTER: Satya Vemula 

PROVIDER: E-GEOD-43771 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress