Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE3968: Puf proteins, RNA co-immunopurification GSE3969: Puf3delta vs. wild type comparison Abstract: Genes encoding RNA-binding proteins are diverse and abundant in eukaryotic genomes. Although some have been shown to have roles in post-transcriptional regulation of the expression of specific genes, few of these proteins have been studied systematically. We have used an affinity tag to isolate each of the five members of the Puf family of RNA-binding proteins in Saccharomyces cerevisiae and DNA microarrays to comprehensively identify the associated mRNAs. Distinct groups of 40-220 different mRNAs with striking common themes in the functions and subcellular localization of the proteins they encode are associated with each of th

ORGANISM(S): Saccharomyces cerevisiae

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PROVIDER: E-GEOD-4393 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress