Effect of PIAS1 on gene expression

ABSTRACT: To study the effect of PIAS1 on transcriptional regulation, we establishedstable PIAS1 shRNA knockdown cells in breast cancer cell line MDA-MB231. By comparing the expression profiles of control vs PIAS1 knockdown cells, we can identify potential PIAS1 target genes involved in breast tumorigenesis. MDA-MB231 Control shRNA and PIAS1 shRNA2 cells were cultured in DMEM plus 10% FBS (DMEM) or SCM for 30 h, and total RNA was used for microarray.

ORGANISM(S): Homo sapiens

SUBMITTER: BIN LIU 

PROVIDER: E-GEOD-44024 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress