Sodium arsenite induced DNA methylation changes in A549 human epithelial lung carcinoma cells

ABSTRACT: Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 M-BM-5M, 0.4 M-BM-5M and 2 M-BM-5M for 1, 2 and 8 weeks. A549 arsenic dose time response study.

ORGANISM(S): Homo sapiens

SUBMITTER: Simone van Breda 

PROVIDER: E-GEOD-44173 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress