Genomic features and regulatory roles of intermediate-size non-coding RNAs in Arabidopsis

ABSTRACT: Recent advances in genome-wide techniques allowed the identification of thousands of non-coding RNAs with various sizes in eukaryotes, some of which have further been shown to serve important functions in many biological processes. However, in model plant Arabidopsis, novel intermediate-sized ncRNAs (im-ncRNAs) (50~300nt) have very limited information. By using a modified isolation strategy combined with deep-sequencing technology, we identified 838 im-ncRNAs in Arabidopsis globally. More than half (58%) are new ncRNA species, mostly evolutionary divergent. Interestingly, annotated protein-coding genes with 5’-UTR derived novel im-ncRNAs tend to be highly expressed. For intergenic im-ncRNAs, their average abundances were comparable to mRNAs in seedlings, but subsets exhibited significantly

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Xuncheng Wang 

PROVIDER: E-GEOD-44235 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress