Gene expression in mouse leukocytes after CAWS administration

ABSTRACT: We performed DNA microarray analyses and compared the difference in the transcriptome between B6 and DBA/2 mice with modest or dramatic sensitivity to CAWS-vasculitis, respectively. Candida albicans water-soluble fraction (CAWS), a mannoprotein-M-NM-2-glucan complex obtained from the culture supernatant of C. albicans NBRC1385, causes CAWS mediated vasculitis (CAWS-vasculitis) with distinct sensitivity among mouse strains. The mouse leukocyte derived from B6 and DBA/2 mice after 2-, 4-, 8-, 9- weeks administration were examined. Each mice was run in singlete or duplicate. Microarray analyses were performed as single-color hybridizations.

ORGANISM(S): Mus musculus

SUBMITTER: Daisuke Okuzaki 

PROVIDER: E-GEOD-44803 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress